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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '001fc9cfe90747751e8209f87c6ec5f46c906b330ef87367b3ed533f0bd33ff9' 
  AND token = '8V7lD1TWzEVE6JBlRX655FJDFJWV0tKRvoyTA1/UCyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}