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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a45b30efd412f7e6c6466a4b40d37d9ab25c44bdf5e03acdee3d7700ae25f7f' 
  AND token = 'V5Y4pz/ZQSE6usU5GS2YzljcqIJmOWmCbiDmHmeiXBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}