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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed282f664a519e1fbe3e07df4f59534490e07861b293d531706bba51fdca60f8' 
  AND token = '990yGhkqqN2mufvkL/XjOxG0LBtVFZ+oonrONtojh64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}