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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33fad2b8190ff0e40701b33de9401fee2a4c3af969a378fe2724a2082576e5c7' 
  AND token = 'BqoU4rviNadmOEKvmskA4148qoFwaXa12ojZTXtlFec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}