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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2165a98079028154050edfe9bc3166048e63e0e15159e7ee713cd49aa867324' 
  AND token = 'uLT3CkX9eBC2Ve55T+7mvlGfF5UmxXbEmYCAWpcUYg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}