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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '541f4fa12c4c54a6c1af2f1099745d7c368ee7f8fc7ec4e6de4655c168f72493' 
  AND token = 'oAha8pwJXtZ2Ur7k1y8/XsFlUM758cYVH/ac93zIUvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}