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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0372a7158f849acff457627d71b906e4b94e4994b9038d1889c24ad80055b00e' 
  AND token = 'HEmOqI8oW0U3IKKDLFKjObnev/5q+cTu9NfVc4PqBQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}