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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe01cdef5c3c2ebad0050f16988f7d97dd20ae4ee30bc817f2f3e04b892abbe5' 
  AND token = 's94We2Ezf4y6/dGxw8Dj4qJXv65q3hBTkzGujXD08dA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}