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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '253aa2b059d06e7f8a4b5016174232dce44bfa7deb76d1622953f3039ae3dea0' 
  AND token = 'laZLuz89YPmhlgBZ+N7fRACv6EEn0WkrSREwFdFU3t4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}