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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f27e51a8937c16851ea5e2bfdce929e05c561d149666f00e4a8df78ca90c310c' 
  AND token = 'MuDGf0PELPSbGMbn8mMmC4TowKzG2mplO2SJMqjzO08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}