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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cf2e24df9774c05e17b50c75c55200a0f10b52c14629f7536ad1ab66cfbdfdd' 
  AND token = '3SPSvCI+p4seA6qV5tSnaMdf5LvIB6tZxet84k/k/UY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}