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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0728279827f867ecc1e547fdcc18425de676a0506961a73b4b95b677e0b3bffb' 
  AND token = 'XicdLfi9znvG20EtQvQPpcigN3Tqydaov5U7Zg3zWZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}