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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bd22e6c7186c4729f67f10a6c5ee2b66787deed0472379767b6db91334174fb' 
  AND token = 'ItLpRxd1pzW6FPjZGbiVFfi6FVMwBeiDq0g9WQSOYUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}