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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4249155baf83cc476187b716ae5ebe279c781bfa9421f4f57506c0dd2a65897' 
  AND token = 'WUU4C4Oyf0OwCjEce9es/iSOA4/ZrRjo1Uhtl1ahty4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}