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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f077fd57bdd1f56ca0a271691ee59e4802c023616f6953a415546ce541d6f1e' 
  AND token = 'HxMCGG1GX+xt55BoyhC0jCaDRHuyaP3yp4WRyFw4Otw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}