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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f45f5960ade1ee1b64ee7cb4194fa3459fec9fe680c12fe45f4689723246d4d' 
  AND token = '2a9grXnz66DZ6YMLDc77FNSeiIpINofsbJwuWY2ZAEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}