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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fe9cdbd03dbc718b8e9813a4b2d15f4fb1767970f748ace0d05209e412a0dcd' 
  AND token = '2GD38WmeiCCytHSXeZTFPWiIwB7+V4ietR0QNTRueuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}