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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e42123ad9fbe7cee1a6930362325ae4917dfee150f6ef319fb07464d52b5996' 
  AND token = 'U24CM6gRcwAbK+rTj4/DL5LuDVgAhyBgT4dXcafoxPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}