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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bca3b01aa46d61f7f38e1bde813fea4bb556d7be4571a4542f2e1d3742f295d9' 
  AND token = 'yXAIyD6C5ymQIAbzcKO+bEGa606dU5C61MVRfSzOGnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}