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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c0f7d3a49efef8d9d156c7d299bdba896288b9c27e0e304a71d2e19a9c928d' 
  AND token = '+b81rJSj6VDXO8PQSy+CPjqottwVhwyi7QJ9UfTh/lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}