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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2504f147b57985464293920e042c3349afd36c0fbd6775eec61c0ccf98d6321' 
  AND token = 'UT515jGFpjfPbFO/U0DokypjQndpv6U2gdf69EssJZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}