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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c00b0aee5148e3bc0efa1f5e4bab85bc462a87afeff113a0b395709684201b0' 
  AND token = 'vpul9PUvAmMh0XIWPq4B8v+3JtO5fC8RE4Ey9a5Gio4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}