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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d205546c47d18afc4d039b03b39357e86c2c2cc06bc2fc348199c3cd36ad65d' 
  AND token = 'uIU0sdLhWHePGYrBBZCnBUiqgJ5O8n9Te1gROajOKuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}