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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca442fe55466fd950c5acfc7c20e5bb1444e6c5200975bf349297a965a39b353' 
  AND token = 'J72C3a9iw8UMy5YoifHZ1VuD7GbMUEdBGI+1hLPQQdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}