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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a53130acafebdad8d2a2c9922b14900cc4b9f05f4235abef4ad27ba88a5dc578' 
  AND token = 'BeH2WL/TDN7K8wDz/+IHXFcIDHyOZ8mihliJEy2kW1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}