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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '552a69dc1c50c1e5217fc1e599214a384d2c632d80477ed883ba745f03dab2f3' 
  AND token = 'mGcX4yWOqjokVankziSBmDWUJaMKgRC5tlvTOPKSyEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}