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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a388b46e70d1a0aa648c7db76c45a6c28b544237b16303ef914081c4a9f22e01' 
  AND token = 'E1wfjU0PaElDGQeuq4kyzHgx+Hs/yaaMGXmYzo0g5nE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}