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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50eaebedeb4f5c72b25eb5e36a93367abff76757118de28cec8973011e68ee6c' 
  AND token = 'diupk9ASwKir4r05+oC05d5fGCOib4GiAXYiil179LI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}