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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11d528e91344d9b5b482034afcb36bece53e8511c58ae8c477979a4e3fa57f15' 
  AND token = '/ACnIHOnntHUTY7oyBGipK3CABxv+D418Nw5NMjhH1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}