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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1642c7d6e6b0723c77b460e0f5a2ac38f141e8051153a2ebfdad5c9b2c8f116' 
  AND token = 'ZlaoqvU+KdJKKNgZti/f+QHTkpdCoPok2pUwYiiXb2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}