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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50f12d86783c2f5c630d674a752c20a4a3e2853fb222b122899a9cbaa231c7d0' 
  AND token = 'DHz1Uhx9o1d1UdXIpgOF54ojTA2NBSlz29qblxtVey0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}