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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7f925f27180f0a5afba837335b3e0cbc38668860b2d9b12a20966fee3254014' 
  AND token = '9TeatFL6fbyqCLOYXhkaTEK3K1sPT1LdV2L8mxqNdCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}