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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51981ab9acbb545f71b9f6537d429aab0a17190126b31280c2e4229a30cc40d0' 
  AND token = 'q+f1qDEXbXiXPHyHOBE575ZaOet20PJU3FRYZDF34P0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}