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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd65ad52dd2d223d267604e38b47ed1e9f675c5617f31e2d6f53587b22b994ec8' 
  AND token = 'IIXKR7UcA7ew1MsHtRbj1WsnJ22pQw8XXCB8CW1afd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}