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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c3d3961d45a7172db8236d40cc9cf1661e516def8c5bfd5b55dadbfa5ed59f7' 
  AND token = '5ijY9egJS8DXKHuaj9slVLv2R5dtkSOjOyMpLgYlLh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}