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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cbb1827fd9a8c666fff694b244863ef443d54858ce46f05a6b6d14ff500f130' 
  AND token = '5JbLSQTFFeg82fT/9iSUd3j+kNJ5V4XCaSLAiXeNM0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}