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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80ee801f7d83fd7308e8ff38a13b0ef51c2467d835e6747f5b94c8ed549fba0a' 
  AND token = 'sHturR963ihM6DyWGWQnQv+AootfdJAtvvPwm4O/660=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}