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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcb8cc26f6271032b02f2d673f32ec7d5b2f44789e3229a4face6717f8f7dc7d' 
  AND token = '3szUhiXf1kNoPZDGRxXY2dSspJ6Tk5aP3l6LDMWFJmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}