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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38406174664b93af9efada91bb05ba9d78d0d89a50f6a32ecfbd86d3c57fbf05' 
  AND token = 'f3EOxXvQ2oUAJ0rybze1z8hQqYQygF1JEcyyTykr6Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}