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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58951bf2bc91029ec78c56b7f2a4198d33d7e3190963013efe5b9c7fe548b72e' 
  AND token = 'G/WsAR4wi4BsEKxrpPOIMKGdHLP+xtk77Z9YtANcS40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}