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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2d9ea24fa5b23074d01fbab177932ca3648c9fe70e48ccf0f290666cb11a92f' 
  AND token = 'j9zwsmElK0a9xxhcb4z3MuTW5Cq4RC8/Nj61TJKjsGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}