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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f7d5ec3412c13985df2279743a52c68a416e52cd4365e4c254bd1a3281d3783' 
  AND token = 'w+r52GSUwy6DHYxErX+pjAwi88L3EdIihuZg/x1m6/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}