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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65c5e9426273dccea750e62b146d8f31e577e0e2966dd5b56020f37b87ee643e' 
  AND token = '481SDKhwHTI4F7IFkaePzcLoqnzhfvdAew0M2Gz9MKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}