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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0ab44bd9d5e8068c6a95e788595294bebbb1237799f2997e67657d730205d4e' 
  AND token = 'CS553Ge+AgRnXBCH+DLDmDbxSw6ANMUH1XEyI2nKzZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}