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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa04b0cc8d7e105800eaa90cf3090a69e515f37a2e4c42870d377fb943272f51' 
  AND token = '9EddXUypjhlgL8SeTnGpClNfD57UO1AkEi0b/KEvJCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}