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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd43947ef68c21407f4813dd59a922816f0d862d976f25baba6f9523e959b2d99' 
  AND token = 'nMwosXZbjTkCurolpLmk8bMV7vTce+ZDyda2Rw5YmYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}