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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0639f5fe5a76216b185e8c689f953d326b49d54f2534c3a8249059bc3e141177' 
  AND token = 'Y+468GXd1bLBu0djF4vUnkiLY3YFEUq5poyuuf3ZyvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}