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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7715e21beff1a752d06b79d7805cdeebb2e256fd16eef469f3785546719b1567' 
  AND token = 'G/Y0Sy5V0lmaP1e+d4akAl1cG1nUk6wRUUyqba/F6XU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}