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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f32b21fb3a68af133ee4d0315d73bb16dbebdcbe44b60dc90303549c54c386b9' 
  AND token = 'lkaDXJzmlrRtaZt5d1KGhj0xqaLvm3EutGvibA0Nbtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}