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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5258181e0d32d02c4e4eb5aee6464ceb78cbe7c364e95d85e676f743625dec6a' 
  AND token = 'hi3gSA1yLGPE/rM68e/DIBwPwVpFg4NJzJEkPOD9HkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}